por Howard Miller.
Sorry if I wasn't clearer. Moodle relies heavily on caching. By default, it will use files in wherever your 'moodledata' resides. If this is NFS then, yes, your site will probably be very slow. For anything beyond a trivial site you should implement a "proper" cache. There are alternatives but Redis is well-used and does a good job.
Once you have that in place, NFS should be absolutely fine. Even for very large sites.